ABSTRACT

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disease and nephrolithiasis is frequent among ADPKD patients compared with general population. In this study, we aimed to review the factors associated with the development of kidney stones in ADPKD patients.

A total of 118 ADPKD patients were retrospectively evaluated. Demographic characteristics, serum biochemistry, and clinical features were compared in stone formers and non-stone formers.

Twenty-eight patients (23.7%) were diagnosed with kidney stones. History of frequent urinary tract infections (UTIs), the presence of liver cyst and gross hematuria were found to be associated with the presence of kidney stones.

According to our findings nephrolithiasis should be kept in mind in ADPKD patients with liver cyst, hematuria, and recurrent UTIs.