, Recep Burak Değirmentepe 1
, Osman Can 1
, Hasan Anıl Atalay 1
, İlter Alkan 1
, Mehmet Gökhan Çulha 1
, Sait Özbir 1
Abstract
Objective: To investigate the relationship between acquired premature ejaculation (PE) and serum vitamin B12 or folic acid levels.
Methods: A total of 93 patients with acquired PE and 69 controls without PE were included the study. All patients fulfilling the criteria of the International Society for Sexual Medicine Committee were considered to have acquired PE. Serum vitamin B12 and folic acid levels were evaluated in all men included in the study.
Results: Compared to controls, vitamin B12 levels were lower in patients with acquired PE (336.5±142.9 pg/mL vs. 356.0±162.5 pg/mL); however, there was no statistically significant difference between the two groups (p=0.576). There was no significant difference in folic acid levels between patients with acquired PE and controls (7.5±3.4 ng/mL vs. 7.3±3.1 ng/mL, p=0.853).
Conclusion: There is no relationship between serum vitamin B12 and folic acid levels and acquired PE. The evaluation of these vitamins should not be recommended to explore the etiology and risk factors of acquired PE.