Objective: This study aims to analyze online information-seeking behaviors of patients in Türkiye regarding adalimumab by using Google Trends data.
Materials and
Methods: Weekly normalized search volume index data between 2016 and 2025 were retrieved for a total of 40 keywords related to “adalimumab,” “humira,” “amgevita,” and 10 thematic domains. The results were normalized with reference to “adalimumab.” Temporal trends and regional (provincial) distributions were evaluated.

Results: The most frequently searched term was “humira,” whereas “adalimumab” attracted relatively limited interest. “Amgevita” was searched at a meaningful level only in certain metropolitan areas. General knowledge, patient experience, and drug pricing emerged as dominant themes. In contrast, searches related to specific indications, such as uveitis and pharmacological features were extremely limited. A statistically significant increase in search interest was observed after 2021 (p<0.001).

Conclusion: Digital information-seeking behaviors about adalimumab have increased and diversified over time. The public appears to use commercial names more frequently than the generic name and shows greater interest in non-medical topics, such as pricing and patient experiences. Awareness of biosimilar medications remains limited and is geographically concentrated in specific provinces.