Objective: Hyperthyroidism is a condition characterized by excessive thyroid hormone production that affects multiple body systems, including the autonomic nervous system. The present study aimed to investigate the relationship between hyperthyroidism and lower urinary tract symptoms (LUTS) in male patients.
Methods: This prospective controlled study. Men newly diagnosed with hyperthyroidism were compared with a control group without any comorbidities. Patients with a history of urinary tract infections, neurogenic bladder diseases, and Benign prostatic hyperplasia /prostate cancer were excluded from the study. International Prostate Symptom Scores (IPSS) between the groups were compared, and the correlation between IPSS scores and free T4 levels was examined.
Results: Of the 58 patients, 20 were in the hyperthyroidism group and 38 were in the control group. The mean total IPSS and mean voiding scores were statistically higher in the hyperthyroidism group than in the control group. A positive correlation was found between IPSS scores and free T4 levels in the hyperthyroidism group.
Conclusion: In patients with hyperthyroidism, increased LUTS are observed. As serum free T4 levels increase, LUTS symptoms also increase.