2Department of Obstetrics and Gynecology, İstanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital, İstanbul, Türkiye
3Department of Obstetrics and Gynecology, İstanbul Gaziosmanpasa Education and Research Hospital, İstanbul, Türkiye
Abstract
Objective: Borderline ovarian tumors (BOTs) are non-invasive tumors with low malignancy potential frequently observed in patients of reproductive age. Therefore, pre-operative differential diagnosis is important in these patients. Our aim was to differentiate benign and BOTs preoperatively using risk of malignancy index (RMI) and tumor markers.
Materials and
Methods: In our study, we retrospectively compared tumor markers and RMI of 85 patients aged between 17 and 84 years with post-operative benign (n=52) and borderline (n=33) ovarian cysts.
Results: In our study, the mean age of the benign group was significantly higher than the borderline group (p=0.001). Ca 125 and RMI values were significantly higher in the borderline group compared to the benign group (p=0.001 and p=0.018). In addition, mucinous tumors had significantly larger tumor diameter than serous tumors in the borderline group (p=0.022).
Conclusion: As a result of our study, since BOTs are seen in young patients of reproductive age, it may be suggested to use Ca125 and RMI for the differential diagnosis of benign and borderline cysts preoperatively.