Original Article

The Evaluation of Insulin Resistance in Patients With Rheumatoid Arthritis

  • Semih Kalyon
  • Serkan Turşak
  • M. Nergis Yanmaz
  • Necati Yenice

Eur Arc Med Res 2011;27(1):23-27

In this study, insulin resistance and it’s relationship with disease activity at patients with rheumatoid arthritis were evaluated. Disease activity was calculated with DAS 28 scale. Waist circumference, CRP, insulin, blood glucose and arterial tension were measured. HOMA IR was calculated. Mann Whitney U, ANOVA and Tukey HSD, Kruskal Wallis test and Pearson corelation analysis were used.

106 patients 12 men and 94 women, were evaluated, and 84 patients had sero-positive rheumatoid arthritis. Mean age (47 yrs), mean waist circumference (93.4 cm), BMI (27.5), mean DAS 28 score (4.5) and mean HOMA IR (2.1) were also calculated.

There was no positive relationship with insulin resistancy and elevated inflammation level. According to DAS 28 score evaluation, there was no correlation between disease activity and insulin resistance.

Keywords: Rheumatoid arthritis, insulin resistance, HOMA, corticosteroid, CRP