Introduction:
To evaluate the efficacy, short and long term complications of single dose intravitrea intravitreal triamcinolone acetonide injection in diabetic macular edema.
Material and Method:
54 eyes of 39 patients with diabetic macular edema were included in the study. The results of the patients who received single dose 4 mg/0,1 ml intravitreal triamcinolone acetonide injection were recorded. Best-corrected visual acuity, central macular thickness, intraocular pressure changes and complications were evaluated.
Results:
At the first month, best-corrected visual acuity increased and central macular thickness decreased significantly from baseline values (p<0.05). Mean central macular thickness before injection, at first and 6th month was 445.11±109.58 μm, 275.87±55.80 μm, 370.78±111.57 μm respectively. At 6th month, central macular thickness increased but did not reach pretreatment values. There was an increase in intraocular pressure at first, second and third months. Subconjonctival hemorrhage (%50), cataract formation (%44), triamcinolone acetonide particules on posterior capsule (%1.85), postoperative hypotony (%1.85), pseudohypopion (%5.55) were recorded as complications.
Conclusion:
Single dose intravitreal triamcinolone acetonide injection improved visual acuity and reduced central macular thickness in diffuse diabetic macular edema. However the effect was transient and complications such as cataract formation and increase in intraocular pressure were seen frequently.
Keywords: cataract, diabetic macular edema, intraocular presseure, intravitreal triamcinolone acetonide