Background:

Usually acetylcholinesterase inhibitors are used for the reversal of non depolarising agents induced neuromuscular blockade. However, these agents have some side effects. Sugammadex is the first and only selective agent for reversing the effect of steroidal neuromuscular blockers and has not any unwanted cholinergic and muscarinic effects unlike acetylcholinesterase inhibitors. There is not sufficient data for sugammadex usage in pregnant patients. In this retrospective study we would like to present our data for sugammadex usage after cesarean sections.

Material and Methods:

During this retrospective study we looked through intraoperative anesthesiology data and patient dossiers of all patients, who had been undergone cesarean section between 01/09/2011 and 01/09/2012 in our clinic. We have recorded patients’ age, ASA score, body weight, pre-pregnancy body weight, duration of the operation, allergic reactions, intraoperative and postoperative complications, previous aneesthesis, comorbide diseases, whether the operation was performed in emergency or elective conditions and the indication of sugammadex administration.

Results:

Sugammedex was used for 16 (1 %) patients from total 1681 cesarean sections. The average operation duration was 52.81±16.83 minutes. 37.5 % of the patients were operated in elective condition and 62.5 % in emergency condition. Sugammadex indication was difficult entubation for 4 patients (25 %), inadequate decurarisation for 7 patients (43.7 %), morbid obesity for 2 patients (12.5 %), HELLP (hemolysis, elevated liver functions and low platelet count) syndrome for 2 patients (12.5 %) and severe hemodynamic instability for 1 patient (6.2 %). We have not experienced any allergic reactions, intraoperative and postoperative complications in Sugammadex used patients.

Sonuç:

Sugammadex was used for 1 % of patients operated for cesarean section. The indication of Sugammadex administration was difficult intubation, morbid obesity, inadequate decurarisation and hemodynamic instability. We have not experienced any compliction due to Sugammadex usage.

Keywords: sugammadex, cesarean section