Original Article

Evaluation of Maternal Magnesium, Calcium and C-reactive Protein Levels in Pregnants With Threatened Preterm Delivery

10.5222/otd.2013.094

  • Gözde Toprakçı Şahin
  • Veli Mihmanlı
  • Nur Çetinkaya
  • Ali Emre Tahaoğlu
  • Soner Pul
  • Taner Mirza
  • Gülşen Karahisar

Received Date: 19.03.2013 Accepted Date: 30.04.2013 Eur Arc Med Res 2013;29(2):94-97

Objective:

Comparison of serum magnesium, calcium and CRP levels in pregnants who were evaluated with the diagnosis of threatened preterm delivery with same gestational aged normal pregnants and to investigate the relationship between serum magnesium, calcium and CRP levels with preterm delivery.

Material and Method:

Study group consisted of 40 pregnants between 20-36 gestation weeks who were hospitalized with the diagnosis of threatened preterm delivery and control group consisted of 40 pregnants who have no obstetric pathology or complaint between September 2011-August 2012 in Okmeydanı Research and Training Hospital. Blood magnesium, calcium and CRP values were compared.

Results:

Magnesium and calcium values of patients in the study group were statiscally significantly lower than the control group (p< 0.01). There was no significant difference in CRP levels between both groups (p>0.05). Calcium levels were statistically significantly higher and CRP levels were significantly lower (p>0.05) in 25 pregnants who were successfully treated with tocolysis, in comparison with the 15 pregnants who had not successful results with tocolysis for threatened preterm delivery (p<0.01). There was no statistically significant difference between the levels of magnesium (p>0.05).

Conclusion:

Serum calcium and magnesium levels are important in the etiology of threatened preterm delivery. Serum calcium and CRP can be useful for predicting the response of tocolysis treatment in pregnants.

Keywords: calcium, CRP, magnesium, premature labor, tocolysis