Original Article

Does Tumor Localization of Operated NSCLC Have an Effect on Relapse and Survival?

10.5222/otd.2018.48802

  • Çağlayan Geredeli

Received Date: 26.03.2017 Accepted Date: 16.11.2017 Eur Arc Med Res 2018;34(2):71-75

Objective:

Our aim was to investigate the effect of tumor localization on relapse and survival in early stage lung cancer.

Material and Methods:

In this multicentered, retrospective study, 182 early stage non small cell lung cancer patients were included between the years of 2012-2015. The localizations of the primary tumor were determined as right upper lobe, right middle lobe, right lower lobe, left upper lobe, left middle lobe and left lower lobe. Overall survival and relapse-free survival rates were compared according to the lobes.

Results:

In total 182 patients were included. The median age was 61 years. Median follow up time was 24.8 months. Of the patients, 38 (20.9%) were stage 1, 82 (45.1%) were stage 2 and 62 (34.1%) were stage 3A. According to tumor localization, 23 (12.6%) were right lower lobe tumors, 13 (7.1%) were right middle lobe tumors, 61 (33.5%) were right upper lobe tumors, 27 (14.8%) were left lower lobe tumors, 58 (31.9%) were left upper lobe tumors. No significant effect was detected on relapse-free survival (p=0.862) and overall survival in terms of tumor localization. (p=0.750).

Conclusion:

In patients with early stage NSCLC, there was no significant difference in relapse-free survival and overall survival in terms of tumor localization.

Keywords: early stage, lung cancer, tumor location