Objective:
In our study, investigation of the effects of blood uric acid level in Acute Coronary Syndromes was aimed.
Material and Method:
The charts of the patients diagnosed with Acute Coronary Syndrome in Coronary Intensive Care Unit and Internal Medicine Department of Okmeydani Training and Research Hospital between October 2012 and February 2013 were retrospectively reviewed. A total of 117 cases were included in the study. 35 cases which are similar to the patient group in terms of age, sex, and chronic diseases were also included as control group. They were compared in terms of age, sex, biochemical parameters, comorbidities, complications, and blood uric acid levels.
Results:
Average uric acid value of patient group was 6.10±1.80 mg/dL. Uric acid levels were high in 33% of cases. Average uric acid levels in control group patients was 6.47±2.16 mg/dl and were high at 45% in the control group. The difference in elevations in uric acid levels were not statistically significant between the two groups. However, acute coronary syndrome in patients with previous heart failure resulted in high uric acid levels and this was found statistically significant.
Discussion:
We think that there was no direct association between uric acid levels and acute coronary syndrome. We found higher uric acid levels in patients with heart failure. We think that this result may be associated with the drugs which were used for heart failure or renal perfusion disorder.
Keywords: acute coronary syndrome, heart failure, risk factors, uric acid